Suboxone

Suboxone is a compound formulation of Buprenorphine and Naloxone.

• Suboxone is a narcotic partial agonist-antagonist.
• Suboxone is a compound, synthetic narcotic analgesic for the treatment of moderate to severe pain.
• Available as an orange, sublingual tablet only to be taken under the tongue until dissolved (2 to 10 min.)
• Available as injection formulation under the brand name of Buprenex.
• Available as a transdermal patch (Europe).
• Suboxone tablets, when crushed, have a reported misuse for intravenous injection and nasal inhalation.
• Suboxone demonstrates a rapid penetration of the blood-brain barrier (due to its ability to dissolve in fats).
• Not intended for pain relief use as a PRN (occasional ‘as needed’ analgesic).
• Suboxone is not recommended for patients with a history of Addison disease, adrenal gland problems, blood or electrolyte problems, chronic obstructive pulmonary disease, breathing or lung problems, or an under-active thyroid.
• Metabolizes in the small intestine and the liver, therefore inappropriate in oral use, but indicated for sublingual (under the tongue) administration.
• Another brand name is Subutex.
• Suboxone is not advised for patients with a history of liver or kidney problems, an enlarged prostate gland, trouble urinating, a blockage of your bladder or urethra, gallbladder problems, or stomach problems.
• Must be taken under doctor's orders, following instructions, since it can be habit forming.
• Increased dosage or chronic use of Suboxone, more than prescribed, can lead to dependency and addiction.
• Regulated in the U.S. under Controlled Substance Act oversight on all manufacturing, importing, possession, and especially distribution of the drug, with supportive therapy recommended to patients with each prescription.
• Suboxone is a Schedule III drug under the United Nations Convention on Psychotropic Substances Classification.
• Demonstrates potential to create moderate physical dependence or a high psychological dependence through chronic use or when abused.
• When taken as Suboxone tablets, doses of Buprenorphine combined with Naloxone come in a 4:1 ratio at 4, 8, 16, and 24 mg.
• International misuse suggests Suboxone closely resembles Schedule II narcotics, except it has lower-dose distribution plus a "ceiling effect''.
• Indications as an opiate analgesic to manage from chronic moderate to acute pain, as well as for perioperative conditions.
• Twenty percent of newborns from mothers treated with Suboxone substitution (for opiate dependence) also show withdrawal syndrome severe enough to necessitate treatment. (i)
• Use with tranquilizers or alcoholic beverages increases risk of adverse side effects, dizziness, poor judgment, physical impairment, and unconsciousness.
• Not to be administered for depression or psychological distress, and not in over-dosage even for its ‘approved indications’.
• Of the 6.4 million Americans misusing prescription drugs, more than 73% misused prescription pain relievers like Suboxone (2006, National Household Survey).

Learn more about Suboxone and The Waismann Method of Rapid Detoxification.